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Learn Physiology Online

Build a body of knowledge on the systems that keep bodies functioning.


In HMX Fundamentals Physiology, you’ll learn essential principles underlying how the human body functions, and see how this knowledge comes into play in real-world scenarios and in clinical settings from the intensive care unit to the cardiac catheterization lab.

This unique online certificate course is led by Harvard Medical School faculty and features:

  • detailed animations and illustrations of medical concepts
  • clinical application videos including real doctor-patient interactions
  • ongoing, rigorous assessments to ensure content mastery

Learn more about the course:

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Course Information

Upcoming course periods

June 4 – August 16, 2024 | Apply now through May 14
Partial tuition waiver application deadline: Tuesday, April 30 at 12 noon US ET (HMX Fundamentals only)

September 3 – November 15, 2024 | Application opens May 15
January 14 – March 28, 2025 | Application opens August 14


Course length

Each course is 10 weeks long. New lessons are released weekly, and material remains available until the course closes. Expect to spend 3-6 hours per course per week.

Course cost

US$800 for an individual course

Partial tuition waivers are available.

What Learners Say

Susan Sandford

Susan Sandford

New York University

“I actually wrote the professor to thank him for making [a subject] that could be really another language so easy to understand.”


Shareef Hussein

Shareef Mohammed Hussein

University of Baghdad Medical School

“I have learned how these concepts are applied in real clinical scenarios, how they can be presented in a patient, and how I can explain why these signs and symptoms are presented in this patient. I know why I would send a patient – for example with asthma, emphysema, or other respiratory diseases – for a pulmonary function test, and how I can interpret this test.”


Lena Levin

Medical device entrepreneur

“I liked specifically this ability for a person who’s not on a medical staff to be virtually in a clinical situation with real clinical patients. Especially I loved the way the physician talked to his patients; it’s not only the clinical knowledge but also how the physician approaches a patient of a certain age or with a certain disease.”

Course Topics

Overview

  • Course introduction
  • Meet the faculty
  • High-level overview

Partial Pressure

  • Partial pressure basics
  • Partial pressures in the lungs and blood

Movement of Body Fluids

  • Osmotic forces
  • Starling forces
  • Body fluid compartments
  • Osmotic forces in the kidney

Flow Through Tubes

  • Ohm’s Law analogy
  • Resistance – series vs. parallel
  • Laminar vs. turbulent flow
  • Air trapping

Compliance

  • Compliance basics
  • Surface tension
  • Laplace’s Law
  • Surface tension and alveoli
  • Elastic and surface forces in the lung

Supply and Demand

  • Aerobic vs. anaerobic metabolism
  • Oxygen delivery
  • Ohm’s Law application
  • Fick principle

Transmural Pressure

  • Transmural pressure basics
  • Flexible tubes
  • Cardiovascular applications
  • Respiratory applications

Dynamic and Steady State Conditions

  • Dynamic and steady state basics
  • Dynamic conditions
  • Pulmonary applications

Acid-Base

  • Acid-base physiology
  • Respiratory acid
  • Metabolic acid
  • Metabolic acid – elimination by kidney

Homeostasis

  • Homeostasis basics
  • Blood pressure
  • Acid-base applications

Exercise – Integration

  • Oxygen in exercise
  • Respiratory quotient
  • Anaerobic threshold

Course Instructor

Richard Schwartzstein, Harvard Medical School and HMX Physiology faculty

Richard M. Schwartzstein, MD

Ellen and Melvin Gordon Professor of Medicine and Medical Education, Harvard Medical School
Director of the Academy, Harvard Medical School
Director of the Center for Education, Beth Israel Deaconess Medical Center
Associate Chief of the Division of Pulmonary and Critical Care Medicine, Beth Israel Deaconess Medical Center