You’ll study 90 credits that covers core chemistry in increasing depth and advanced practical work.You will also have a choice of specialist optional modules to provide a further 30 credits.
Advanced Laboratory Techniques
This course aims to teach advanced experimental techniques in chemistry.
To provide experience in the recording, analysis and reporting of physical data.
To put into practice the methods of accessing, assessing and critically appraising the chemical literature.
Bioinorganic and Metal Coordination Chemistry
The aim of this module is to provide you with an understanding of coordination chemistry in the context of macrocyclic, supramolecular and bioinorganic chemistry and its applications in metal extraction and synthesis.
You will gain an appreciation of the importance of metals in biological systems, and be able to explain the relationship between the structure of the active centres of metallo-proteins and enzymes and their biological functions.
The module is assessed by a two-hour written exam.
Catalysis
This module aims to provide a framework for understanding the action of heterogeneous catalysts in terms of adsorption/desorption processes and for understanding catalyst promotion in terms of chemical and structural phenomenon and also describes a wide variety of homogeneous catalytic processes based on organo-transition metal chemistry.
Chemical Bonding and Reactivity
To provide a fundamental understanding of molecular structure and of the requirements for reactivity.
To introduce modern electronic structure theory and demonstrate how it can be applied to determine properties such as molecular structure, spectroscopy and reactivity.
Organometallic and Asymmetric Synthesis
This module will introduce you to a range of reagents and synthetic methodology. You will learn how to describe how it is applied to the synthesis of organic target molecules.
By the end of the module you will know how the use of protecting groups can be used to enable complex molecule synthesis and how modern palladium-mediated cross-coupling reactions can be used to synthesise useful organic molecules.
Your problem-solving and written communication skills will be developed.
Pericyclics and Reactive Intermediates
Use of frontier molecular orbital analysis to explain and predict stereochemical and regiochemical outcomes of pericyclic reactions (Woodward-Hoffmann rules etc).
Examples will be drawn from Diels-Alder reactions, cycloadditions [4+2] and [2+2], [3,3]-sigmatropic rearrangements (eg Claisen and Cope), [2,3]-sigmatropic rearrangements (eg Wittig and Mislow-Evans).
Generation and use of reactive intermediates in synthesis (ie radicals, carbenes, nitrenes).
Solids, Interfaces and Surfaces
This course aims to teach the relationship between structure and properties of solids, structure of Solids and characterisation.
It aims to teach a general introduction to Interfaces and Surfaces.
Communicating Chemistry
A classroom-based module for learning key skills including communication, presentation, team-working, active listening, time management and prioritisation. Increased transferable skills which will enhance employability and confidence.
Provision of classroom experience if considering teaching as a potential career.
Chemical Biology and Enzymes
Students should gain a good appreciation of the applications for a range of enzymological, chemical and molecular biological techniques to probe cellular processes and catalysis at the forefront in chemical biology research.
This module represents a culmination of principles and techniques from a biophysical, molecular, biochemical and genetic perspective.
Topics in Inorganic Chemistry
This module covers inorganic mechanisms and the overarching fundamental principles of greener and sustainable chemistry as applied to processes, inorganic reaction mechanisms, and discussion on the theme of greener and sustainable chemistry
Structure Determination Methods
A general introduction to lasers, including laser radiation and its properties will be given.
A number of current laser spectroscopic methods will be reviewed, which allow the determination of vibrational frequencies and structures.
Examples will cover ground and excited state neutral molecules, radicals and complexes, as well as cations of these.
An introduction to modern diffraction methods will be given, involving neutrons, electrons and X-rays.
Applications will cover solids (crystalline and amorphous), liquids and gases.
Throughout, there will be extensive examples from the research literature.
Protein Folding and Biospectroscopy
This module will develop an understanding of protein structure, stability, design and methods of structural analysis. In addition you will understand the protein folding problem and experimental approaches to the analysis of protein folding kinetics and the application of site-directed mutagenesis.
You will also be expected to develop a number of spectroscopic experimental techniques to probe protein structures.
There will be two hours of lectures a week.
Contemporary Drug Discovery
What influence does a chemist have in the modern drug discovery process? And how can chemists use their knowledge to aid the development of new therapeutics? In this module you will apply knowledge of how chemical structures influence drug potency, pharmacokinetics, and their safety. You will gain insight onto the developmental process of designing a drug and their action once they have reached their desired target.
You’ll study:
- Drug Targets and How They Bind
- Measuring Drug Activity
- Lead Compounds and Strategies for Improving Drug Potency and Selectivity
- Pharmacokinetics (Absorption, Distribution, Metabolism and Elimination)
- Drug Design in a Safe Manner
- Desired Drug Properties
Drug discovery: the development of new medicines
You’ll explore the vital role of chemistry in drug discovery, involving discussions of the way chemical structure influences the molecular properties, biological activity, and toxicity of drugs.
Many examples from case histories of successful medicines will be used to illustrate the underlying chemical principles.
This module is taught through nine interactive workshops presented by experienced medicinal chemists from GlaxoSmithKline and staff in the School of Chemistry.
The above is a sample of the typical modules we offer but is not intended to be construed and/or relied upon as a definitive list of the modules that will be available in any given year. Modules (including methods of assessment) may change or be updated, or modules may be cancelled, over the duration of the course due to a number of reasons such as curriculum developments or staffing changes. Please refer to the
module catalogue for information on available modules. This content was last updated on